客户文献

2020：

基础医学研究所-代谢流-细胞-Neuro-oncology  GC-MS代谢流  IF 10.091

Fu Y, Wang DD, Wang HS, Zhang JM, et al. TSPO deficiency induces mitochondrial dysfunction, leading to hypoxia, angiogenesis, and a growth-promoting metabolic shift toward glycolysis in glioblastoma. Neuro-oncology, 2020.

深圳农科院-植物方向-拟南芥-Plant cell-LC-MS靶向定量(植物激素) IF 8.631

Liu F, Zhang H, Ding L, Xiang Y, et al. REVERSAL OF RDO5 1, a Homolog of rice Seed dormancy 4, Interacts with bHLH57 and Controls ABA Biosynthesis and Seed Dormancy in Arabidopsis. Plant cell, 2020.

中山医院-代谢流-细胞-Immunology-GC-MS代谢流  IF 4.147

Dong Z, Li RS, Xu L, Ge JB, et al. Histone Hyperacetylation Mediates Enhanced IL-1β Production in LPS/IFN-γ stimulated Macrophages. Immunology, 2020.

2019：

复旦大学附属华山医院-乙酰辅酶A-细胞-Cell Metabolism-LC-MS靶向定量  IF 22.415

Lu M, Zhu WW, Qin LX, et al. ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition. Cell Metabolism, 2019.

河南大学-动物方向-血清-International Journal of Nanomedicine-GC-MS非靶向 IF 4.471

Yang YJ, Lv SY, Ji SP, et al. Toxicity and serum metabolomics investigation of Mn-doped ZnS quantum dots in mice. International Journal of Nanomedicine, 2019.

龙华医院-动物方向（非靶向）-血清组织粪便-Scientific reports-GC-MS 非靶向IF 4.011

Li M, Dang YQ, Zhang L, et al. Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice. Scientific reports, 2019.

上海东方肝胆医院-肝癌-组织-Hepatology-LC-MS靶向定量  IF 14.971

Liu J, Jiang JH, He YF, Wang HY, et al. Global DNA 5-Hydroxymethylcytosine and 5-Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma. Hepatology, 2019.

上海中医药大学-肠道菌群(代谢组)-血清-Journal of proteome research-GC-MS非靶向 IF 4.245

Gu Y, Liu C, Zheng NN, Li HK, et al. Metabolic and Gut Microbial Characterization of Obesity-Prone Mice under a High-Fat Diet. Journal of proteome research, 2019.

生化所-代谢流-细胞-Nature communications-GC-MS   IF 11.878

Liu RL, Li WF, Yang WW, et al. Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance. Nature communications, 2019.

协和医院-免疫-细胞-Science Immunology-GC-MS非靶向与LC-MS靶向 IF 10.551

Liu Y, You YL, Cao XT, et al. N6-methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication. Science Immunology, 2019.

中国农业大学-药物毒性研究（脂质组）-组织-FASEB Journal  IF 5.391

Yang X, Xu WT, He XY, et al. Precision toxicology shows that troxerutin alleviates ochratoxin A–induced renal lipotoxicity. FASEB Journal, 2019.

中国医科院病原所-寨卡病毒(液质脂质组)-细胞组织-Science Advances  IF 12.804

Zhou J, Chi XJ, Cheng M, Yang W, et al. Zika virus degrades the -3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis. Science Advances, 2019.

2018：

北京蛋白质研究中心-癌症-细胞-Cancer Letters-GC-MS非靶向和脂质组 IF 6.508

Cai MJ, Sun X, Chen H, et al. Disruption of peroxisome function leads to metabolic stress, mTOR inhibition, and lethality in liver cancer cells. Cancer Letters, 2018.

上海公共卫生临床中心-艾滋病-血浆-Clinical Infectious Diseases- LC-MS靶向定量 IF 9.055

Chen J, Xun JN, Ji YJ, Lu HZ, et al. Plasma Indoleamine 2, 3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy. Clinical Infectious Diseases, 2018.

上海瑞金医院-二型糖尿病-抗生素-肠道菌群（短链脂肪酸 胆汁酸）-血浆粪便-Journal of Endocrinology-GC-MS和 LC-MS 靶向定量 IF 4.381

Fu LH, Qiu YX, Gao XF, Gu YY, et al. The delayed effects of antibiotics in type 2 diabetes, friend or foe? Journal of Endocrinology, 2018.

生化所-代谢流-细胞-Molecular cell -GC-MS  IF 14.548

Zhang YJ, Yu GZ, Chu HY, Yang WW, et al. Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis. Molecular cell, 2018.

四川大学-植物缺磷研究-植物组织-Plant Journal-LC-MS非靶向 IF 5.726

Luo BW, Ma P, Nie Z, Gao SB, et al. Metabolite profiling and genome-wide association studies reveal response mechanisms of phosphorus deficiency in maize seedling. Plant Journal, 2018.

西北农林科技大学-动物方向-细胞-Agricultural and food chemistry-GC-MS非靶向 IF 3.571

Liu YL, Shen J, Yang X, Sun QZ, Yang XJ. Folic Acid Reduced Triglycerides Deposition in Primary Chicken Hepatocytes. Agricultural and food chemistry, 2018.

植保所-微生物芽孢杆菌-Journal of Industrial Microbiology & Biotechnology-GC-MS非靶向  IF 2.993

Wang JQ, Guo RJ, Wang WC, Ma GZ, Li SD. Insight into the surfactin production of Bacillus velezensis B006 through metabolomics analysis. Journal of Industrial Microbiology & Biotechnology, 2018.

中国农业大学-肠道微生物-(短链脂肪酸 芳香类物质)-粪便-Journal of Nutritional Biochemistry-GC-MS非靶向和靶向定量 IF 4.49

Li DT, Wang P, Wang PP, Hu XS, Chen F. Gut microbiota promotes production of aromatic metabolites through degradation of barley leaf fiber. Journal of Nutritional Biochemistry, 2018.

2017：

华南农业大学-病毒-细胞-Frontiers in Microbiology-GC-MS非靶向 IF 4.259

Gou HC, Zhao MQ, Chen JD, et al. Metabolic Profiles in Cell Lines Infected with Classical Swine Fever Virus. Frontiers in Microbiology, 2017.

华中农业大学-寄生虫代谢流-细胞样本-Cellular Microbiology-GC-MS代谢流 IF 4.288

Xia NB, Yang JC, Shen B, et al. Functional analysis of Toxoplasma lactate dehydrogenases suggests critical roles of lactate fermentation for parasite growth in vivo. Cellular Microbiology, 2017.

上海海洋大学-视黄酸-组织-Nature Genetics-LC-MS靶向定量（视黄酸） IF 25.455

Shao CW, Bao BL, Xie ZY, Chen SL, et al. The genome and transcriptome of Japanese flounder provide insights into flatfish asymmetry. Nature Genetics, 2017.

瑞金医院-肠道菌群课题-血浆-Nature Communications-LC-MS靶向定量（胆汁酸） IF 11.878

Gu YY, Wang XK, Ning G, et al. Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment. Nature Communications, 2017.

瑞金医院-肠道菌群课题-血清-Nature Medicine-GC-MS和LC-MS多平台非靶向联合分析 IF 30.641

Liu RX, Hong J, Gu YY, Ning G, et al. Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention. Nature Medicine, 2017.

瑞金医院-肥胖相关课题-细胞-Endocrine-LC-MS靶向定量（AEA） IF 3.296

Ning TL, Zhou YY, Hong J, Ning G, et al. Genetic interaction of DGAT2 and FAAH in the development of human obesity. Endocrine, 2017.

上海中医药大学-肠道菌群-血清-Journal of proteome research-GC-MS非靶向 LC-MS靶向定量（胆汁酸）  IF 4.245

He XY, Zheng NN, Li HK, et al. Gut microbiota modulation attenuated the hypolipidemic effect of simvastatin in high-fat/cholesterol-diet fed mice. Journal of proteome research, 2017.

上海中医药大学-中药毒性研究-尿液-Toxicological Sciences-GC-MS非靶向IF 3.564

Hu XQ, Shen JJ, Li HK, et al. Urinary Time- or Dose-Dependent Metabolic Biomarkers of Aristolochic Acid-Induced Nephrotoxicity in Rats. Toxicological Sciences, 2017.

中科院-鳞状细胞癌研究-血清-Biochemical and Biophysical Research Communications  LC-MS靶向定量（色氨酸代谢途径）IF 2.705

Cheng J, Jin H, Zheng GY, et al. Disturbed tryptophan metabolism correlating to progression and metastasis of esophageal squamous cell carcinoma. Biochemical and Biophysical Research Communications, 2017.

2016：

江南大学-菌微生物大肠杆-Plos One-GC-MS非靶向 IF 3.234

Liu LN, Duan XG, Wu J. L-Tryptophan Production in Escherichia coli Improved by Weakening the Pta-AckA Pathway. Plos One, 2016.

江南大学-菌微生物大肠杆-Journal of Biotechnology-GC-MS非靶向 IF 3.163

Liu LN, Duan XG, Wu J.Modulating the direction of carbon flow in Escherichia coli to improvel-tryptophan production by inactivating the global regulator FruR. Journal of Biotechnology, 2016.

上海中医药大学-高血脂症药物治疗研究-大鼠血清肝脏粪便-Journal of Tranlational Medicine-GC-MS非靶向 IF 4.098

Li M, Shu XB, Ji G, et al. Integrative analysis of metabolome and gut microbiota in dietinduced hyperlipidemic rats treated with berberine compounds. Journal of Tranlational Medicine, 2016.

扬州大学-肠道菌群-血浆-Scientific Reports GC-MS靶向（短链脂肪酸） IF 4.011

Liu L, Zhao X, Gong DQ, et al. Prosteatotic and Protective Components in a Unique Model of Fatty Liver: Gut Microbiota and Suppressed Complement System. Scientific Reports, 2016.

2014：

长海医院-食管癌-血清-Journal of proteome research-GC-MS非靶向 IF 4.245

Jin H, Qiao F, Chen L, Gao XF, et al.Serum Metabolomic Signatures of Lymph Node Metastasis of Esophageal Squamous Cell Carcinoma. J Proteome Res, 2014.